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Through this book, your health care providers will have access to algorithms that offer guidelines for precisely changing your diabetes medications to enhance weight loss, especially to avoid hypoglycemia (low blood glucose levels).

Exercise volumes of 150 minutes per week of moderate-intensity or 75 minutes per week of vigorous-intensity aerobic exercise, such as recommended in the 2008 Physical Activity Guidelines Advisory Committee Report, further reduce CVD mortality.

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Cationic drugs eliminated by renal tubular secretion, furosemide, nifedipine: may increase metformin levels.

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Patients should be advised to avoid exercise when their insulin is at peak effect.

There have been postmarketing reports of worsening renal function in patients taking sitagliptin with or without metformin, including acute renal failure, sometimes requiring dialysis.

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