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According to the prescribing information, during clinical trials of Zocor, patients reported experiencing several gastrointestinal adverse reactions associated with treatment.
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Phan T, Mcleod JG, Pollard JD, Peiris O, Rohan A, Halpern JP "Peripheral neuropathy associated with simvastatin.
IMPORTANT SAFETY INFORMATION Who should not take EVOTAZ?
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Statins, including Baycol, Lipitor and Zocor.
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Orsi A, Sherman O, Woldeselassie "Simvastatin-associated memory loss.
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Drawing from a sample of 437 subjects with moderately abnormal liver tests at baseline, possibly associated with NAFLD, 227 who were treated with statins showed substantial improvement in liver tests, while 210 not treated with statins displayed further increases in liver enzyme concentrations.
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All joy has been taken from me from the pain, the terrible fatigue, and the depression.
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the American Journal of Cardiology published the study "Effects of Maximal Atorvastatin and Rosuvastatin Treatment on Markers of Glucose Homeostasis and Inflammation" conducted by Thongtang and colleagues from Tufts University in Boston.
Fluvastatin (Lescol); Atorvastatin (Lipitor); Lovastatin (Mevacor); Pravastatin (Pravachol); Simvastatin ( Zocor); Rosuvastatin (Crestor); Pitavastatin (Livalo).
However, safety and efficacy of simvastatin in children younger than 10 years of age have not been established.
Class Review on HMG-CoA Reductase Inhibitors (Statins).
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If you have additional questions or concerns, regarding treatment with Zocor (simvastatin), contact your health care provider.
CoQ10 depletion is also a factor in cognitive dysfunction and other neurological consequences of these drugs.
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Since I've only been taking it a short period of time, the side effects are minimal so far but because I've taken Crestor and Provastatin prior to Zetia, I'm leery of these medicines.
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To better understand how carotid artery disease affects the brain, a basic review of the anatomy of the circulation system of the brain follows.
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But the Food and Drug Administration (FDA) is just now catching on to that.
The FDA removed this long-standing warning in 2012 and ruled that patients taking statins no longer need routine monitoring of liver enzymes, but instead can have liver enzymes tested before starting the drugs, and then only as clinically needed, which seems reprehensibly irresponsible.
Although the magnitude of this effect was small, it would nevertheless be expected to have important economic implications given the large cost differences between generic and brand-name medications ().
The combined use of simvastatin in patients receiving diltiazem should not exceed 40 mg daily unless the clinical benefit is likely to outweigh the increased risk of myopathy.
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Finally, policy levers, such as tiered formularies, have been the most effective strategies for driving patients to adopt generics, but current copayment differentials between generic and brand-name medications may not be sufficient to motivate generic drug use by some patients (); thus, a need for further research about these behavior change tools also remains.
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Report any side effects with simvastatin to FDA's MedWatch program using the information at the bottom of the page in the "Contact Us" box.
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