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One weight loss trial showed no difference between individuals who took Garcinia cambogia. Despite the popularity of Garcinia cambogia, it's not easy to monitor how successful supplements containing it are. And clinical trials have revealed it's not dangerous to take Garcinia cambogia extract by mouth — at least the span of the studies, for 12 weeks. Garcinia cambogia has side effects - it may lower a person's blood sugar , so it can socialize with diabetes treatments.