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One weight loss trial demonstrated no difference between folks who took those who took a placebo pill and Garcinia cambogia. Despite the popularity of Garcinia cambogia, it is hard to track how effective supplements comprising it are. And clinical trials have revealed it's not dangerous to take Garcinia cambogia extract for 12 weeks, the span of the studies at least by mouth —. Garcinia cambogia has side effects - it may lower someone's blood sugar , so it can socialize with diabetes treatments.