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The primary outcome was a reduction of more than 25% in lesion size at 20 weeks.

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Comment: Some outcomes did not appear to be affected by blinding issues because they were objectively assessed (complete regression after treatment, partial regression after treatment) and they were appraised as low risk of bias.

Previously, she was assistant professor of dermatology and director of dermatology clinical trials at the University of Arkansas for Medical Sciences, Little Rock.

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The UVA spectrum is absorbed by melanin and, through free-radical transfer, affects cellular deoxyribonucleic acid (DNA).

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The patients applied a thin layer of study medication to the lesions and let it remain overnight without a cover twice a week for a period of 16 weeks.

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Risk factors for the development of these eruptions include advanced age, increased number of concomitant medications, female gender, immunosuppression (i.

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Although not evaluated in this study, differences in expression levels of TLRs or other receptors that interact with Leishmania, the maturation stage (), and the functional integrity of permanent cell lines () may account for differences observed in the responses to parasite opsonization elicited in primary macrophages and macrophage cell lines.

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The method of claim 18, wherein the response rate is measured after the end of treatment with the treatment method or the control method as a composite response rate assessment of subjects having both (a) an elimination of clinical evidence of basal cell carcinoma, and (b) a complete histological response.

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