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My cardiologist diagnosed me with stable angina about a year ago. At that time I experienced tightness in my chest and pain when breathing after some exercises. That considerable spoiled my life as I enjoy climbing and often stay in the mountains with my friends. He put me on some medication and the on second day of taking it I developed some itching and rash on my arms. However I decided that was from mosquitoes or some strange food and paid no attention and naturally continued on the medication. The rash wouldn't disappear and having come back home I visited a dermatologist. He said it was not a skin disorder and probably some intolerance of a new drug. I went to the cardiologist again and he told me to stop taking the medication and prescribed Ranolazine. With this med I had no itching or rash. The angina also created considerably less problems that before. No I could control the pain and had no more problems with breathing. It's been two months since I have started on Ranolazine and I am absolutely ok with it.

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The average bioavailability of Isosorbide dinitrate is about 25%; most studies have observed progressive increases in bioavailability during chronic therapy.

Other US Food and Drug Administration-approved uses are specific to each beta blocker and include stable and unstable angina, atrial arrhythmias, bleeding esophageal varices, coronary artery disease, asymptomatic and symptomatic heart failure, migraine, and secondary prevention of post-myocardial infarction.

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The objective of this systematic review was to quantify the clinical benefit of BB, CCBs, long-acting nitrates (LANs), ranolazine, trimetazidine, ivabradine or nicorandil added to first-line monotherapy for stable coronary artery disease.

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